Anti-Periostin (Pan) Antibody

Descrição detalhada : Periostin, also known as PN, or Osteoblast-specific factor 2 (OSF-2), and encoded by the gene POSTN/OSF2, is a secreted extracellular matrix protein that appears to be involved in inducing cell attachment and spreading as well as cell adhesion. In bone, Periostin enhances mineralization and assists in the incorporation of BMP1 protein into the fibronectin extracellular matrix of connective tissues. Periostin is preferentially expressed in periosteum and periodontal ligaments but can also be found expressed in developing heart and other tissues. Periostin is also over expressed in many cancers where is contributes to a growth-supportive role for such cancers and also aids in chemoresistance for cancers cells through the activation of the PI3K/Akt/surviving pathway.
Sinónimos : Periostin, PN, Osteoblast-specific factor 2, OSF-2
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA