Anti-BTG3 Antibody

REF : ABC508
Marca : Sigma-Aldrich
Descrição :Anti-BTG3 Antibody from rabbit, purified by affinity chromatography
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Descrição detalhada : BTG3 is a tumor suppression protein because overexpression impairs serum-induced cell cycle progression from G0/G1 to the S phase in vitro. BTG3 is often down regulated in cancer cell lines, and thus BTG3 is a target for enhanced cancer therapy. In normal cells BTG3 inhibits cell proliferation, cell invasion, and angiogenesis, and also regulates cell-cycle progression and differentiation in a variety of cell types. Developmentally BTG3 is normally expressed primarily in the brain and CNS during development where is modulates cell proliferation. In the adult expression is high in ovary, testis, prostate, thymus and lung. It is not expressed strongly in many cancers.
Sinónimos : Protein BTG3, Abundant in neuroepithelium area protein, BTG family member 3, Protein Tob5
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA