Protein L from Peptostreptococcus magnus

Descrição detalhada : Protein L protein binds immunoglobulin (Ig) light chains in a wide range of species including human, mouse, rat, pig, hamster, and chicken, but has low affinity for Igs from guinea pig, and rabbit. This bacterial protein interacts with Ig light chains without blocking the antigen binding site of the Igs . Thus, protein L can be used for the detection of IgG, IgM, IgA, IgE and IgD containing ? light chains. It may also be used to detect Fab and scFv fragments containing ? light chains. Protein L does not bind to bovine, sheep or goat Igs. Hence, when bound to a solid support (sepharose) , protein L may be used to directly purify monoclonal antibodies from media supplemented with BSA or FCS, and also to directly purify human or mouse antibodies from goat, bovine or sheep proteins. rProtein L is a recombinant form of the native protein and contains two Ig binding protein L fragments., Protein L is an immunoglobulin light chain-binding protein. It is expressed by a few anaerobic bacterial species, such as Peptostreptococcus magnus.
Armazenamento : 2-8C
Embalagem : 1X5MG