Bone Morphogenetic Protein 4 human

Descrição detalhada : BMP are members of the TGF-beta superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF-beta family proteins, BMPs are highly conserved across animal species. Mature BMPs are 30-38 kDa proteins that assume a TGF-beta-like cysteine knot configuration. Unlike TGF-beta, BMPs do not form latent complexes with their propeptide counterparts. Most BMPs are homodimers, but bioactive natural heterodimers have been reported., Bone morphogenetic protein 4 (BMP4) is a member of the transforming growth factor-? (TGF-?) superfamily. It is a glycoprotein with cysteine knot and exists as homodimer corresponding to a molecular mass of 26 kDa. BMP4 is mapped to human chromosome 14q22.2. BMP4 is expressed in embryonic and adult tissues. It is synthesized in the endoplasmic reticulum and in Golgi, it undergoes posttranslational modifications.
Sinónimos : BMP-4
Armazenamento : -20C
Embalagem : 1X1EA