Anti-STAT6 antibody produced in rabbit

REF : HPA001861-100UL
Marca : Sigma-Aldrich
Descrição :Anti-STAT6 antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution
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Descrição detalhada : Signal transducers and activators of transcription 6 (STAT6) belongs to the family of DNA binding proteins. It is mainly involved with Interleukin-4 (IL-4)-mediated gene expression. Src homology-2 domain (SH2) domain of STAT6 binds to docking sites of IL-4 receptor ? to get tyrosine-phosphorylated by the receptor-associated janus kinase (JAK). This binding activates SATAT6 and it forms homodimer. Further, it translocates to the nucleus for adhering with the high affinity STAT-binding elements (SBE) of IL-4/IL-13.
Sinónimos : STAT Antibody - Anti-STAT6 antibody produced in rabbit; Stat6 Antibody; Anti-IL-4 Stat antibody produced in rabbit; Anti-Signal transducer and activator of transcription 6 antibody produced in rabbit
Armazenamento : -20C
Embalagem : 1X100UL