17-DMAG – CAS 467214-21-7 – Calbiochem

REF : 100069-500UG
Marca : Sigma-Aldrich
Descrição :17-DMAG - CAS 467214-21-7 - Calbiochem A potent antitumor analog of 17-AAG that binds to the ATPase site of human Hsp90alpha with high affinity and displays excellent bioavailability and aqueous solubility.
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Descrição detalhada : A cell-permeable, water soluble, potent anti-tumor analog of 17-AAG (Cat. No. 100068) that binds to the ATPase site of human Hsp90alpha with high affinity (GI50 = 51 nM for 17-DMAG vs. 120 nM for 17-AAG in the NCI 60-cell panel in vitro activity screen)., A potent antitumor analog of 17-AAG (Cat. No. 100068) that binds to the ATPase site of human Hsp90alpha with high affinity (GI50 = 51 nM for 17-DMAG vs. 120 nM for 17-AAG in the NCI 60-cell panel in vitro activity screen), and displays excellent bioavailability and aqueous solubility.
Sinónimos : 17-DMAG - CAS 467214-21-7 - Calbiochem; NSC 707545, 17-Desmethoxy-17-N,N-dimethylaminoethylamino-geldanamycin, HCl, 17-N,N-Dimethylaminoethylamino-17-demethoxy-geldanamycin, HCl, 17DMAG
Fórmula molecula r: C32H48N4O8 · xHCl
Armazenamento : -20C
Embalagem : 1X500UG