Akt Inhibitor VI, Akt-in – Calbiochem

Descrição detalhada : A reversible 15-mer peptide derived from proto-oncogene TCL1 (amino acids 10-24) that acts as a specific inhibitor of Akt. Shown to bind to Akt-PH domain (Kd ~18 µM) and interfere with the Akt-phosphoinositide interaction, thus hindering membrane translocation from the cytosol and downstream biological responses., A reversible 15-mer peptide derived from the amino acids 10-24 of the proto-oncogene TCL1 (TCL10-24) and acts as a specific inhibitor of Akt. Shown to bind to the Akt-PH domain (Kd ~18 µM) and interfere with the Akt-phosphoinositide interaction. This peptide, when made cell-permeable (Cat. No. 124014), has been shown to hinder Akt membrane translocation from the cytosol and subsequent downstream biological responses.
Sinónimos : Akt Inhibitor VI, Akt-in - Calbiochem; TCL1?????, H-AVTDHPDRLWAWEKF-OH
Fórmula molecula r: C88H123N23O23
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X2MG