Amiloride, Hydrochloride – CAS 2016-88-8 – Calbiochem

Descrição detalhada : An inhibitor of angiogenesis. At low concentrations, acts as a potent and specific inhibitor of transmembrane Na+ entry and Na+/H+ ATPase. Inhibits smooth muscle responses to contractile stimuli. Blocks palytoxin-induced conductance in skeletal muscle. Reduces the electrical potential across tubular epithelium. At higher concentrations, blocks the Na+/H+ exchange pathway., An inhibitor of angiogenesis. Inhibits capillary morphogenesis completely and reversibly at approximately 130 µM. At low concentrations, acts as a potent and specific inhibitor of transmembrane Na+ entry and Na+,K+-ATPase. Also acts as an inhibitor of urokinase-type plasminogen activator (uPA). Blocks smooth muscle responses to contractile stimuli and palytoxin-induced conductance in skeletal muscle. Reduces electrical potential across tubular epithelium. At higher concentrations, blocks the Na+/H+ exchange pathway.
Sinónimos : Amiloride, Hydrochloride - CAS 2016-88-8 - Calbiochem; Acid-Sensing Ion Channel Modulator I, ASIC Channel Modulator I
Fórmula molecula r: C6H8ClN7O · xHCl
Armazenamento : 10-30C
Embalagem : 1X100MG