AMPK Activator – CAS 849727-81-7 – Calbiochem
REF : 171256-5MG
Marca : Sigma-Aldrich
Descrição :AMPK Activator - CAS 849727-81-7 - Calbiochem The AMPK Activator, also referenced under CAS 849727-81-7, modulates the biological activity of AMPK. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
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Categoria : Small Molecules
Descrição detalhada : A cell-permeable furancarboxylic acid compound that activates celular AMP-activated protein kinase (AMPK) activity by inhibiting mitochondrial complex I, and thus elevating intracellular AMP level. Shown to enhance glucose uptake in L6 myocytes (EC50 = 11.7 µM). Reduces blood glucose levels in ZDF rats in vivo (oral dose 30-100 mg/kg). Displays negligible cytotoxicity at pharmacological doses.
Sinónimos : AMPK Activator - CAS 849727-81-7 - Calbiochem; 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid, D942, AMPK Signaling Activator I; 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid, D942, AMPK Signaling Activator I
Fórmula molecula r: C22H21FO4
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG
Sinónimos : AMPK Activator - CAS 849727-81-7 - Calbiochem; 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid, D942, AMPK Signaling Activator I; 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid, D942, AMPK Signaling Activator I
Fórmula molecula r: C22H21FO4
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG