Anaphase-Promoting Complex Inhibitor, TAME – CAS 1784-03-8 – Calbiochem
REF : 172104-50MG
Marca : Sigma-Aldrich
Descrição :Anaphase-Promoting Complex Inhibitor, TAME - CAS 1784-03-8 - Calbiochem The Anaphase-Promoting Complex Inhibitor, TAME, also referenced under CAS 1784-03-8, controls the biological activity of Anaphase-Promoting Complex. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
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Categoria : Small Molecules
Descrição detalhada : TAME is a potent ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation by directly binding to APC and disrupts the IR-tail-dependent interactions between APC and its activator proteins Cdc20 or Cdh1. It stabilizes APC substrates and is shown to inhibit cyclin proteolysis in mitotic Xenopus egg extract with an IC50 = 12 µM.
Sinónimos : Anaphase-Promoting Complex Inhibitor, TAME - CAS 1784-03-8 - Calbiochem; TAME hydrochloride, APC/C Inhibitor I, APC/C-Cdc20 Interaction Inhibitor I, Cyclosome Inhibitor I
Fórmula molecula r: C14H22N4O4S · xHCl
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X50MG
Sinónimos : Anaphase-Promoting Complex Inhibitor, TAME - CAS 1784-03-8 - Calbiochem; TAME hydrochloride, APC/C Inhibitor I, APC/C-Cdc20 Interaction Inhibitor I, Cyclosome Inhibitor I
Fórmula molecula r: C14H22N4O4S · xHCl
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X50MG