Angiogenesis Inhibitor – CAS 186611-44-9 – Calbiochem

REF : 175580-10MG
Marca : Sigma-Aldrich
Descrição :Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem The Angiogenesis Inhibitor, also referenced under CAS 186611-44-9, controls the biological activity of Angiogenesis. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable indolinone compound that displays anti-angiogenesis properties (30% inhibition of control at 10 µM in an in vitro rat aortic ring model ) with a potency that is comparable to that of SU5416 (Cat. No. 676487; 22% inhibition of control at 10 µM). Acts as a moderate ATP-competitive inhibitor of hEGF-R tyrosine kinase activity (54% inhibition at 10 µM)., A cell-permeable indolinone compound that displays anti-angiogenesis properties (30% inhibition of control at 10 µM in an in vitro rat aortic ring model). The potency has been reported to be comparable to that of SU5416 (Cat. No. 676487; 22% inhibition of control at 10 µM). Acts as a moderate ATP-competitive inhibitor of hEGF-R tyrosine kinase activity (54% inhibition at 10 µM).
Sinónimos : Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem; ( Z,E)-3-(Imidazol-4-ylmethylene)indolin-2-one; (Z,E)-3-(Imidazol-4-ylmethylene)indolin-2-one
Fórmula molecula r: C12H9N3O
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG