Anti-Actin, alpha-Smooth Muscle – Alkaline Phosphatase antibody, Mouse monoclonal

Descrição detalhada : The antibody (also known as anti-alpha-Sm-1) is specific for the single isoform of alpha-smooth muscle actin. It reacts specifically with alpha-smooth muscle actin in immunoblotting assays and labels smooth muscle cells in frozen or formalin-fixed, paraffin-embedded tissue sections., Actin is a highly conserved protein that is a major component of both the cytoskeletal and contractile structures in all cell types. It varies in amount, being related to the type of differentiation and to the functional state of cells and tissues. Actin can be found in two different forms of aggregation, the globular or the fibrillar state, and at least six distinct isoforms occur in vertebrates. The actins exhibit over 90% sequence homology, but each isoform has a unique NH2-terminal sequence. The isoforms are comprised of three alpha actins (skeletal, cardiac, smooth), one beta actin (beta-non-muscle) and two gamma actins (gamma smooth muscle and gamma non-muscle).
Sinónimos : Monoclonal Anti-Actin, alpha-Smooth Muscle; Monoclonal Anti-Actin, alpha-Smooth Muscle - Alkaline Phosphatase antibody produced in mouse; SMA
Armazenamento : 2-8C
Embalagem : 1X.2ML