Anti-Ago3 Antibody, clone 4B1-F6

Descrição detalhada : Eukaryotic translation initiation factor 2C 3, Ago3, belongs to the argonaute family and contains 1 PAZ and 1 Piwi domain. Ago3 is indicated to play a role in the RNA interference (RNAi) pathway, which is important for heterochromatin formation and accurate chromosome segregation. Unlike Ago1 and Ago2, Ago3 and AG04 do not possess the ability to dissociate miRNA duplexes in a minimal in vitro system. Re-introduction of any Ago variant into embyronic (ES) cells deficient for expression of all four Ago variants will rescue miRNA silencing defects and reduce apoptosis.
Sinónimos : eIF-2C 3, eIF2C 3, FLJ12765, MGC86946
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA