Anti-alpha B-crystallin Antibody

Descrição detalhada : Alpha B-crystallin is a major structural protein in the vertebrate eye lens, but is also found in cardiac and skeletal muscles, kidney, and brain. Alpha B-crystallin is also found to be a component of Rosenthal fibers and a consistent tissue marker of epileptic foci. It occurs as large aggregates of up to 106 Da, composed of two proteins, alphaA- and alphaB-crystallin. The alphaA gene encodes a polypeptide of 173 residues, while alphaB-crystallin gene encodes a 175 residue polypeptide. alphaB-crystallin, like the small heat shock proteins (sHsp's), is induced by heat or osmotic shock and is upregulated by stress. alpha-crystallin and the sHsp's protect other proteins from heat-induced aggregation. The two other crystallin families, beta and ɣ, are homologous to each other but not to the alpha-family or the sHsp's.
Sinónimos : Alpha-crystallin B chain, Alpha(B)-crystallin, Heat shock protein beta-5, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA