Anti-alpha-Tubulin antibody, Mouse monoclonal

Descrição detalhada : Anti-alpha-Tubulin antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the hybridoma AA13 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with rat brain tubulin., Tubulin ? 1a (TUBA1A) is a member of ?-tubulin gene family. It is encoded by the gene mapped to human chromosome 12q13.12. Tubulin ? 1a is a vital structural subunit of microtubules that are temporarily expressed in almost all post-mitotic neurons during neuronal development.The encoded protein structure contains core of two ?-sheets enclosed by ?-helices. TUBA1A is characterized with an amino-terminal domain with the guanine nucleotide-binding region, an intermediate domain associated with interprotofilament lateral contacts and the modulation of tubulin curvature, and a carboxy-terminal domain that contains region involved in interacting with microtubule-associated proteins (MAPs) and molecular motors, such as kinesins and dynein.
Sinónimos : Anti-Tuba1a; Anti-Tubulin, alpha1A
Armazenamento : -20C
Embalagem : 1X25UL