Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit

REF : A8717-.2ML
Marca : Sigma-Aldrich
Descrição :Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution
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Descrição detalhada : Amyloid precursor proteins (APPs) are transmembrane glycoproteins that are found in a wide range of tissues. APP is expressed in the brain. It is located on human chromosome 21. APPs have 3 main isoforms, namely, APP695, APP751 and APP770 that are derived from alternative splicing events in cells. Accumulation of the cleavage products of APP, such as the ?-amyloid peptide, can cause Alzheimer?s disease., The immunogen sequence is identical to rat and mouse APP695 and in the APP isoforms APP751 and APP770. The antibody recognizes APP695, APP751 and APP770.
Sinónimos : APP antibody; Anti-APP
Armazenamento : -20C
Embalagem : 1X.2ML