Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit
REF : B0681-.2ML
Marca : Sigma-Aldrich
Descrição :Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution
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Categoria : Antibodies
Descrição detalhada : The membrane-associated aspartic protease BACE-1 (?-site APP cleaving enzyme, Asp2 or memapsin 2) has been identified as ?-secretase. BACE-1 constitutes the predominant ?-secretase activity in human brain tissue. It is highly expressed in neurons, the major site of A? generation. BACE-1 is localized within the Golgi and endosomal compartments, among the several intracellular sites where A? is thought to be produced. BACE-1 is initially an inactive proenzyme and localized in endoplasmic reticulum.
Sinónimos : Anti-beta-Site APP Cleaving Enzyme
Armazenamento : -20C
Embalagem : 1X.2ML
Sinónimos : Anti-beta-Site APP Cleaving Enzyme
Armazenamento : -20C
Embalagem : 1X.2ML
