Anti-beta-Catenin-Cy3 antibody, Mouse monoclonal

Descrição detalhada : The gene ?-catenin (CTNNB1) is mapped to human chromosome 3p21. The protein localizes to the cytoplasm and the nucleus. ?-catenin is also present at the centrosomes., Anti-?-Catenin-Cy3 antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the 15B8 hybridoma, produced by fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with recombinant chicken catenin. ?-catenin is 92 kDa. ?-catenin protein is composed of a series of protein-protein interaction motifs that allow it to function as a scaffold. The N-terminus domain contains the binding site for ?-catenin as well as phosphorylation sites recognized by Glycogen synthase kinase 3 beta (GSK3?) and the C-terminus contains the transcriptional activation domain and binding site for Teashirt.
Sinónimos : Monoclonal Anti-beta-Catenin
Armazenamento : 2-8C
Embalagem : 1X200UL