Anti-beta-Tubulin antibody, Mouse monoclonal

REF : T8328-25UL
Marca : Sigma-Aldrich
Descrição :Anti-beta-Tubulin antibody, Mouse monoclonal ~2.0 mg/mL, clone AA2, purified from hybridoma cell culture
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Descrição detalhada : Tubulin, a 100kDa protein is present in all cells as a heterodimer of two similar polypeptides ? and ?, which assemble to form microtubules. Monoclonal anti-?-tubulin antibody can be used to visualize HRP signal using enhanced chemiluminescence., ?-tubulin belongs to the subfamily of tubulins, which are the major building blocks of microtubules. ?-tubulin has a molecular weight of 55kDa. ?-tubulin structure is characterized with core of two ?-sheets enclosed by ?-helices. It also contains an N-terminal domain with the guanine nucleotide-binding region, an intermediate domain with taxol-binding site and a C-terminal domain that contains the binding surface for molecular motor proteins. Human ?-tubulin consists of seven isoforms (?I (class I), ?II (class II), ?III (class III), ?IVa (class IVa), ?IVb (class IVb), ?V (class V) and ?VI (class VI))., Tubulin ?III (TUBB3) is a constituent of microtubules. It is expressed in mature neurons. It is located on human chromosome 16q24.
Sinónimos : Beta Tubulin Antibody Sigma; Beta Tubulin Antibody Sigma - Monoclonal Anti-beta-Tubulin antibody produced in mouse; Anti-TUBB; Anti-Tubulin, beta
Armazenamento : -20C
Embalagem : 1X25UL