Anti-Cytoplasmic FMR1-interacting protein 1 Antibody

Descrição detalhada : Cytoplasmic FMR1-interacting protein 1 (CYFIP1) is a member of the CYFIP family. It is a component of the CYFIP1-EIF4E-FMR1 complex, a regulatory complex for translational repression that binds to the mRNA cap. Within the complex, CYFIP1 serves as an adapter between the other two components and upregulates the translation repression activity of FMR1. It regulates epithelial morphogenesis, binds F-actin, and is a component in the development and formation of axon outgrowth, lamellipodia, protrusions, and membrane ruffles. Through its interaction with RAC1, CYFIP1 regulates the activity of WASP family members. CYFIP1 is associated with Prader-Willi/Angelman syndromes and may also have a role in autism.
Sinónimos : cytoplasmic FMR1 interacting protein 1, Specifically Rac1-associated protein 1, cytoplasmic FMRP interacting protein 1, cytoplasmic FMR1-interacting protein 1, selective hybridizing clone
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA