Anti-Desmin antibody produced in rabbit

Descrição detalhada : Desmin is an intermediate filament protein found mainly in skeletal, cardiac, and smooth muscle cells. It acts as a marker for tumor origin. It also facilitates mechanical support for muscles, mitochondrial localization, myofibrillogenesis, gene expression regulation, and intracellular signalling. Anti-desmin antibody can be used for immunocytochemical localization of intermediate filaments in all types of muscle cells. It can also be used to stain a wide desmin band of 50,000 to 55,000 molecular weight using immunoblotting assays. Rabbit anti-desmin antibody reacts specifically with desmin in bovine, mouse, chicken and human., Desmin is mapped to human chromosome 2q35. The desmin protein comprises of a head domain, four ?-helical segments, three non-helical rod segments and a tail domain. It exists as dimer and tetramer assemblies. In smooth and striated muscles, desmin is localized in the periphery of Z-disk.
Sinónimos : Anti-CDCD3; Anti-CSM1; Anti-CSM2; Anti-LGMD1D; Anti-LGMD1E; Anti-LGMD2R
Armazenamento : -20C
Embalagem : 1X1ML