Anti-dimethyl-Histone H4 (Arg3) Asymmetric Antibody

REF : 07-213-I
Marca : Sigma-Aldrich
Descrição :Anti-dimethyl-Histone H4 (Arg3) Asymmetric Antibody from rabbit, purified by affinity chromatography
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Descrição detalhada : Histone H4 has multiple isoform names including H4/A through H4/N, and is encoded by multiple genes in the genome named HIST1H4A through HIST1H4N/H4/A or H4FA through H4/L and HIST2H4A, HIST2H4B, and HIST4H4. Histone H4 is a critical component of chromatin and the nucleosome. Histone H4 forms a multimeric cluster with the other histone members to regulate chromatin and DNA structure within the nucleus. Histone H4 is a target of much post-translational modification including acetylation, methylation, phosphorylation, ubiquitination, sumoylation, crotonylation (male germ cells only and marks testis specific genes) and citrullination. Acetylation of histone H4 on lysine 16 (H4-K16Ac) is the most prevalent and reversible posttranslational chromatin modification in eukaryotes for histone H4 and it and the other modifications help control chromatin structure and the protein interactions of histone H4.
Sinónimos : Histone H4
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA