Anti-Dopamine beta Hydroxylase Antibody, clone 4F10.2

Descrição detalhada : Dopamine Beta Hydroxylase (DBH), the structural locus encoding DbetaH enzyme, is a major quantitative trait locus influencing plasma DbetaH activity, with one single nucleotide polymorphism (SNP) accounting for up to 50% of the variance. Mutations at DBH appear to be responsible for the rare syndrome of DbetaH deficiency. It functions as the only enzyme involved in the synthesis of small-molecule neurotransmitters that is membrane-bound, making norepinephrine and epinephrine the only transmitters synthesized inside vesicles. It is expressed in noradrenergic nerve terminals of the central and peripheral nervous systems, as well as in chromaffin cells of the adrenal medulla.
Sinónimos : DBH
Armazenamento : -20°C
Embalagem : 1X1EA