Anti-ELKS antibody, Mouse monoclonal

REF : E4531-200UL
Marca : Sigma-Aldrich
Descrição :Anti-ELKS antibody, Mouse monoclonal clone ELKS-30, purified from hybridoma cell culture
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Descrição detalhada : ELKS/RAB6-interacting/CAST family member 1 is a protein encoded by the ERC1 gene in humans. It encodes for a synaptic factor and is found in the smallest region of overlap., Monoclonal Anti-ELKS (mouse IgG2a isotype) is derived from the hybridoma ELKS-30 produced by the fusion of mouse myeloma cells (NS1 cells) and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a fragment of human ELKS. ELKS, also known as KIAA1081, is an essential regulatory subunit of the IKK complex. It was named ELKS since 44.1% of the sequence is composed of glutamic acid (E), leucine (L), lysine (K) and serine (S) residues. The protein contains 948 amino acids with nine -helical coiled-coil domains including periodic heptad repeats that predict dimer formation. Its highest expression is in heart, placenta, lung, brain, thyroid and testis.
Sinónimos : Anti-KIAA1081
Armazenamento : -20C
Embalagem : 1X200UL