Anti-FGF23 Antibody, clone 278-2

Descrição detalhada : Fibroblast growth factor 23 (FGF-23) is also called Phosphatonin and Tumor-derived hypophosphatemia-inducing factor. FGF-23 belongs to the heparin-binding growth factors family and has several important functions including: regulation of phosphate homeostasis, inhibition of renal tubular phosphate transport, upregulation of EGR1 expression, regulation of vitamin-D metabolism, and negative regulation of osteoblast differentiation and matrix mineralization. FGF-23 is expressed in osteogenic cells, adult trabecular bone, osteocytes and flattened bone-lining cells (inactive osteoblasts). Defects in FGF23 can lead to autosomal dominant hypophosphataemic rickets (ADHR) and hyperphosphatemic familial tumoral calcinosis (HFTC).
Sinónimos : Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor, Fibroblast growth factor 23 N-terminal peptide, Fibroblast growth factor 23 C-terminal peptide
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA