Anti-G-protein coupled receptor 56 (GPR56) Antibody, clone H11

Descrição detalhada : G-protein coupled receptor 56 (GPR56) is a ubiquitous adhesion receptor, which belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. It is abundantly expressed in the in thyroid gland, brain, heart, and various tumor cells. Previous studies have suggested that GPR56 may inhibit the progression and metastasis of melanomas by interaction with extracellular-matrix proteins, such as Tissue Transglutaminase. GPR56 also plays a role in regulating VEGF production and angiogenesis via a PKCalpha-mediated pathway. GPR56 also plays a critical role in the development of the frontal cortex; previous studies have reported that mutations in GPR56 result in disorganized cortical lamination, which is most pronounced in the frontal cortex. This condition is known as bilateral frontoparietal polymicrogyria or BFPP.
Sinónimos : G protein-coupled receptor 56, 7-transmembrane protein with no EGF-like N-terminal domains-1, Protein TM7XN1, G-protein coupled receptor 56
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA