Anti-G3BP antibody produced in rabbit

Descrição detalhada : G3BP is a RNA-binding protein that contains a RNA binding domain, the RRM-type domain, at the carboxyl-terminal. The N-terminal domain is homologous to nuclear transporter factor 2 (NTF2) and the central domain is rich in acidic residues. The RRM domain is involved in the binding of G3BP to specific RNA sequences. This helps G3BP to function as a CA dinucleotide-specific endoribonuclease. G3BP?s subcellular localization and protein-protein interactions are mediated by the phosphorylation of G3BP at Ser149, near NTF2-like domain. G3BP is found in abundance in many kinds of malignant tumors such as lung, colon, gastric, and breast cancer.
Sinónimos : Anti-G3BP1; Anti-GAP SH3 domain-binding protein; Anti-HDH-VIII; Anti-Ras-GTPase-activating protein SH3-domain binding protein 1; Anti-human DNA helicase VIII
Armazenamento : -20C
Embalagem : 1X200UL