Anti-GLUT9 Antibody

Descrição detalhada : GLUT9, also known as Glucose transporter type 9 or GLUT-9, and encoded by the gene SLC2A9/GLUT9, is a member of the sugar transport family that primarily transports urate and fructose; GLUT9 does also transport glucose but at a lower rate than its preferred sugars. GLUT9 also plays a role in urate reabsorption by the proximal tubules of the kidney. GLUT9 is localized to the plasma membrane. GLUT9 is most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. GLUT9 is also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Defects in GLUT9 may be associated with Hypouricemia renal 2 (RHUC2) a disorder characterized by impaired uric acid reabsorption at the apical membrane of proximal renal tubule cells, and high urinary urate excretion.
Sinónimos : Solute carrier family 2, facilitated glucose transporter member 9, Glucose transporter type 9, GLUT-9
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA