Anti-Histone Deacetylase 7 (HDAC7) antibody, Mouse monoclonal

Descrição detalhada : Monoclonal Anti-Histone Deacetylase 7 (HDAC7) (mouse IgG1 isotype) is derived from the hybridoma HDAC7-97 produced by the fusion of mouse myeloma cells (NS1cells) and splenocytes from BALB/c mice. Histone deacetylases (HDACs) are part of transcriptional corepressor complexes. HDAC7 is a member of Mammalian HDAC family. It is localized mainly to the cell nucleus, it is also found in the cytoplasm., Histone deacetylases (HDACs) are competing enzymes, belonging to histone deacetylase family. There are two classes of HDACs with six to seven different types of HDACs proteins. HDAC1,HDAC2 and HDAC3 belong to Class I HDACs and HDAC4, HDAC6, and HDAC7 belong to Class II HDACs. Class I HDACs consists of a single deacetylase domain at the N-termini and diversified C-terminal regions, while Class II contains a deacetylase domain at C-terminal position. HDAC7 is predominantly found in the cell nucleus and slightly in cytoplasm. HDAC7 shuttles between these two regions and this is controlled by 14-3-3 protein and calmodulin-dependent kinase I (CaMKI)
Sinónimos : Anti-HDAC7
Armazenamento : -20C
Embalagem : 1X200UL