Anti-Human IgG (gamma-chain specific)-R-Phycoerythrin antibody produced in goat

Descrição detalhada : Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. It consists of a gamma (?) heavy chain in the constant (C) region. The primary structure of the antibody contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and also resides inside the chains., Affinity isolated antigen specific antibody is obtained from goat anti-human IgG antiserum by immunospecific purification which removes essentially all goat serum proteins, including immunoglobulins, which do not specifically bind to the ?-chain of human IgG. Goat anti-human IgG is conjugated to Sigma R-Phycoerythrin (Product No. P8912) by a modification of the method of Kronick Unbound phycoerythrin is removed by gel filtration chromatography Specificity for the ?-chain of human IgG is determined by Ouchterlony Double Diffusion (ODD). The antibody preparation is specific for human IgG when tested against purified human IgA, IgG, IgM, Bence Jones ? and Bence Jones Lambda myeloma proteins, prior to conjugation Identity and purity of the antibody is established by immunoelectrophoresis (IEP), prior to conjugation Electrophoresis of the antibody preparation followed by diffusion versus anti-goat IgG and anti-goat whole serum results in single arcs of precipitation., Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders Anti-Human IgG (?-chain specific)-R-Phycoerythrin antibody is specific for human IgG when tested against purified human IgA, IgG, IgM, and Bence Jones ? and ? myeloma proteins.
Sinónimos : Goat Anti-Human IgG (gamma-chain specific)?R-PE
Armazenamento : 2-8C
Embalagem : 1X.5ML