Anti-Integrin B4 Antibody, clone ASC-8, Azide & Ascites Free

Descrição detalhada : Integrin proteins couple the ECM outside of a cell to the cytoskeleton inside of the cell. Which ECM protein binds and what signals are conveyed depend upon the particular makeup of the integrin pair being expressed. Functional integrin receptors are made up of two protein chains linked by disulfide bonds, an alpha chain and a beta chain. Integrin beta 4, also known as CD104, or GP160 is one of eight different beta chains, however beta 4 integrin is part of only one principal integrin receptor, integrin alpha6beta4. This receptor is expressed in endothelium, epithelium, and perineurium tissues of several organs as well as fibroblasts and Schwann cells but not in blood or lymphatic cells. Integrin alpha6beta4 is the laminin receptor and is critical for cellular polarity and motility.
Sinónimos : Integrin beta-4, Integrin B4, Integrin Beta4, GP150, CD104
Armazenamento : -20°C
Embalagem : 1X1EA