Anti-Integrin beta7 Antibody, clone TN114

Descrição detalhada : Integrin beta7 is an adhesion molecule belonging to the integrin beta chain family. It forms heterodimers with the alpha subunit, most notably the integrin alpha4 and alphaE subunits, functioning to mediate migration and homing of lymphocytes to the gut-associated lymphoid tissue (GALT). The heterodimer formed with alpha4, alpha4beta7, is specifically involved in the homing and migration of lymphocytes to the gut, while alphaEbeta7 is involved in the binding of T lymphocytes to epithelial cells and is induced by TGFbeta1. Integrin beta7 has been observed in several different leukocyte lines.
Sinónimos : integrin, beta 7, integrin beta 7 subunit, Gut homing receptor beta subunit
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA