Anti-Interleukin-11 antibody produced in goat

REF : I5270-1MG
Marca : Sigma-Aldrich
Descrição :Anti-Interleukin-11 antibody produced in goat IgG fraction of antiserum, lyophilized powder
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Descrição detalhada : Interleukin-11 (IL-11) is a pleotropic cytokine that belongs to the IL-6 family. The effects of IL-11 include hemopoiesis, macrophage differentiation and thrombopoiesis. Many cell types including osteoblasts, trophoblasts, fibroblasts, chondrocytes and a variety of tissue such as brain, gut, spinal cord and testis secrete IL-11. The cellular effects of IL-11 are mediated by a multimeric complex consisting of IL-11Ralpha and gp130Rbeta subunits. The pathways activated by IL-11 include JAK/STAT, Ras/MAPK and Grb2 signaling. IL-11 plays a major role in inflammatory responses, immune responses by regulating the production of IgG by B cells and in tumorigenesis-related inflammation Anti-Interleukin-11 antibody specifically reacts with human IL-11.
Sinónimos : Anti-IL-11
Armazenamento : -20C
Embalagem : 1X1MG