Anti-IRGM Antibody

Descrição detalhada : Immunity-related GTPase family M protein (IRGM), also known as Interferon-inducible protein 1 (IFI1) and LPS-stimulated RAW 264.7 macrophage protein 47 homolog (LRG-47), is a member of the interferon-inducible GTPase family. It induces autophagy and generates large autolysosomal organelles as a mechanism for the elimination of intracellular Mycobacterium tuberculosis. IRGM is expressed in colon, small bowel, and peripheral blood leukocytes. Mutations in IRGM have been assoicated with inflammatory bowel disease type 19 which is subdivided into Crohn's disease and ulcerative colitis phenotypes.
Sinónimos : IRGM Antibody, Immunity related GTPase family, IFL1, IRGM1, LRG47, LRG-47
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA