Anti-ITGB5 antibody produced in rabbit

Descrição detalhada : ?ntegrins, heterodimeric trans-membrane matrix receptors, are mainly involved in the signal transduction and attachments to extra cellular matrix (ECM).†† In ECM they act as a mediator of cell adhesion.† In human, at least 18 ? and eight ? subunits have been found.† ITGB5 (integrin subunit ? 5) helps in facilitation of cancer cell migration, anchorage-independent growth and tumor angiogenesis. Integrin is activated by G-protein-coupled receptors, resulting in the phosphorylation of cytoplasmic domain of the ? subunit. The coupled ? and ? cytoplasmic tails are responsible for maintaining integrin in inactive state.
Sinónimos : Anti-Integrin beta5-precursor antibody produced in rabbit
Armazenamento : -20C
Embalagem : 1X100UL