Anti-Laminin-1 A&B chains Antibody, cross region, clone AL-2

Descrição detalhada : Laminins are secreted glycoproteins incorporated into cell-associated extracellular matrices and an integral part of the structural scaffolding in most animal tissues. The laminin protein is made up of three polypeptide chains; alpha, beta and gamma, accounting for its flexibility in connecting various molecules. When originally characterized, laminin-1 clone AL-2 reacted with Engelbreth-Holm-Swarm (EHS) mouse laminin A & B chains on the long arm near the cross region, (Skubitz, 1987). More recently, investigations, (Sche'ele, 2006) have shown that the clone binds laminin beta1 under reducing conditions as well as native ELISAs and that the affinity is increased by the presence of the laminin alpha1 chain. Thus there is significant laminin beta1 reactivity with clone AL-2.
Sinónimos : laminin alpha1, laminin beta1
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA