Anti-LIMS1, clone 5G7 Antibody

Descrição detalhada : LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1), also known as Particularly interesting new Cys-His protein 1 (PINCH-1; PINCH1; PINCH), or Renal carcinoma antigen NY-REN-48 is an adaptor protein which contains five LIM domains, or double zinc fingers. LIMS1 is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that Lims1 may play a role in integrin-mediated cell adhesion or spreading.
Sinónimos : LIM and senescent cell antigen-like-containing domain protein 1, Particularly interesting new Cys-His protein 1, PINCH-1, Renal carcinoma antigen NY-REN-48
Armazenamento : -20°C
Embalagem : 1X1EA