Anti-MDMX antibody, Mouse monoclonal

Descrição detalhada : Double minute 4 protein or MDMX is a nuclear protein. The gene encoding it is localized on human chromosome 1q32.1., Monoclonal Anti-MDMDX (mouse IgG1 isotype) is derived from the hybridoma MDMX-82 produced by the fusion of mouse myeloma cells (NS1 cells) and splenocytes from BALB/c mice. MDMX belongs to the MDM family. The MDMX/ mouse double minute 4 (MDM4) gene encode a 490 amino acid protein. MDMX comprises a putative nuclear localization signal, a really interesting new gene (RING) finger domain in the C terminal and a p53-binding domain in the N terminal. MDMX has significant structural similarity to MDM2 E3 ubiquitin ligase.
Sinónimos : Anti-HDMX; Anti-MDM4; Anti-p53 Binding Protein
Armazenamento : -20C
Embalagem : 1X200UL