Anti-MEF2C antibody produced in rabbit

Descrição detalhada : MEF2C (myocyte enhancer factor 2C) belongs to Myocyte enhancer factor 2 (MEF2) protein family, which in turn belongs to a family of transcriptional regulators called MADS (MCMI, agamous, deficiens, serum response factor)-box. Four different forms of MEF2 protein are found in vertebrates, namely, MEF2A, MEF2B, MEF2C, and MEF2D. MEF2C is predominantly expressed in brain and skeletal muscle. It shares the common DNA-binding and dimerization domain present at the N-terminal, with other MEF2 proteins. Alternative splicing produces two MEF2C variants, which lack ? exon. These MEF2C?- are ubiquitously expressed, but at a lower level than MEF2C?+ variants. MEF2C?- variants are also less expressed in other tissues, as opposed to brain and heart. Alternative splicing also produces either MEF2C?+ or MEF2C?- isoforms. MEF2C?- is the major isoform expressed in differentiating myocytes and adult tissues. MEF2C is mapped to chromosome 5q14.3.
Sinónimos : Anti-Myocyte-specific enhancer factor 2C antibody produced in rabbit
Armazenamento : -20C
Embalagem : 1X100UL