Anti-MMP-2 Antibody, pro and active form, clone A-Gel VC2

Descrição detalhada : MMPs have a common mode of activation, a conserved amino acid sequence in the putative metal-binding active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). These MMPs and TIMPs could be expressed by either the cancer or the stromal cells. There is a cooperation between tumor and stromal cells, in particular for the production of 72-kD type IV collagenase, involved in the disruption of basement membranes. A lack of TIMP-1 expression from invasive cancer cells could also contribute to matrix destruction.
Sinónimos : Gelatinase A, 72 kDa Type IV Collagenase
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA