Anti-mTOR antibody produced in rabbit

Descrição detalhada : mTOR is an evolutionary conserved serine/threonine kinase that belongs to the phosphoinositol kinase-related kinase (PIKK) family. This kinase regulates cell growth by initiation of translation in response to nutrients such as amino acids (primarily leucine), growth factors, mitogens and insulin. Translational initiation is mediated by mTOR through S6K1 activation and 4E-BP1 inhibition. mTOR may also modulate several cellular functions such as actin organization, secretion, membrane trafficking, protein degradation, protein kinase C signaling, tRNA synthesis and ribosome biogenesis. Anti-mTOR antibody is specific for human, mouse and rat mTOR (289 kDa).
Sinónimos : Anti-FKBP-12 rapamycin associated protein; Anti-FRAP; Anti-RAFT; Anti-SEP
Armazenamento : -20C
Embalagem : 1X200UL