Anti-Neuropeptide Y (NPY) antibody produced in rabbit

Descrição detalhada : Anti-Neuropeptide Y (NPY) is developed in rabbits using synthetic neuropeptide Y (porcine) conjugated to keyhole limpet hemocyanin (KLH) as the immunogen., Neuropeptide Y (NPY), a 36-amino acid peptide amide, is a major regulatory neuropeptide widely distributed in the mammalian central (CNS) and peripheral nervous systems (PNS). NPY belongs to the pancreatic polypeptide family of peptides which are characterized by a common tertiary structure. Within this family, an intestinal peptide hormone, peptide YY (PYY), is most closely related to NPY. In the CNS, NPY is involved in regulation of blood pressure, memory processing, circadian rhythm, and stimulation of food intake. In the PNS, NPY has potent vasoconstrictor activity and acts as a neurotransmitter/neuromodulator of sympathetic neurons and adrenal glands. NPY is one of the most abundant peptides found in the CNS, widely distributed in the brain. High levels of NPY are present in the cerebral cortex, amygdaloid nuclei, hippocampal formation, and hypothalamus. In the PNS, NPY is found mainly in sympathetic neurons that innervate vascular smooth muscle, heart, and urogenital tract. The biological actions of NPY in the brain and periphery are mediated by at least two different NPY receptors, designated Y1 and Y2 receptor subtypes.
Sinónimos : NPY Antibody - Anti-Neuropeptide Y (NPY) antibody produced in rabbit; Npy Antibody
Armazenamento : -20C
Embalagem : 1X.2ML