Anti-NLRP6 (NALP6) Antibody

Descrição detalhada : NRLP6 (NALP6) (also known as PYRIN-containing Apaf-1-like protein 5 or PYPAF5) belongs to a family of proteins that play a critical role in apoptosis and in inflammatory signaling. Its expression is highly restricted to granulocytes and T-cells. Co-expression of NALP6 with ASC results in synergistic activation of caspase-1-dependent cytokine processing, subsequent NF-kB activation, and downstream recruitment of PYPAF5 to punctate structures in the cytoplasm. Overlapping genes in NALP6/PYPAF5 locus encode two V2-type vasopressin isoreceptors: angiotensin-vasopressin receptor (AVR) and non-AVR.
Sinónimos : NACHT, PYRIN-containing APAF1-like protein 5, LRR and PYD domains-containing protein 6
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA