Anti-OPA1, clone 1OPA-1A8 Antibody

Descrição detalhada : OPA1 (optic atrophy 1) is a dynamin-related GTPase that plays a role in genome preservation and mitochondrial morphology. Localization of OPA1 is thought to be anchored to the inner membrane of the mitochondria. OPA1 is highly expressed in inner and outer retinal neurons and is important for normal mitochondrial function in those cells. Mutations in OPA1 are the major cause of autosomal dominant optic atrophy. Recent research has found that OPA1 also has the ability to protect neurons from excitotoxic injury and could be a potential clinical target to increase endurance of neurons post brain damage.
Sinónimos : Dynamin-like 120 kDa protein, mitochondrial, Large GTP-binding protein, LargeG, Optic atrophy protein 1 homolog, Dynamin-like 120 kDa protein, form S1
Armazenamento : -20°C
Embalagem : 1X1EA