Anti-phospho-Glycogen Synthase Kinase 3alpha/beta (pTyr279/216) antibody produced in rabbit

Descrição detalhada : GSK-3 functions a serine-threonine kinase and modulates a wide range of cellular activities such as cell signaling, cell cycle, cell growth and differentiation. Mammalian GSK-3 has two isoforms, namely, GSK-3? and GSK-3 ?. GSK-3? has been implicated in Alzheimer's disease, whereas both, GSK-3? and GSK-3? have been implicated in leukemia . Anti-phospho-Glycogen Synthase Kinase 3?/? (p(Tyr279/216)) antibody is specific for phosphorylated forms of GSK-3? (51 kDa) and GSK-3? (47 kDa) that contain a phosphate moiety on tyrosine 279 and 216 respectively. The antibody does not bind to non-tyrosine phosphorylated GSK-3?/? protein. The product recognizes human, mouse and rat GSK-3?/?.
Sinónimos : Anti-phospho-GSK alpha/beta (pTyr279/216)
Armazenamento : -20C
Embalagem : 1X50UG