Anti-phospho-PAK1 (Ser199/Ser204) Antibody

Descrição detalhada : p21-activated kinases (PAK) are Ser/Thr kinases, which are activated by, and are effectors of Rho family of GTPases. As such, they are implicated in Actin polymerization and activation of the stress-activated kinase cascades. PAK1 is phosphorylated by cdk5, resulting in its inhibition. PAK2 can be activated by Caspase-cleavage in addition to p21-binding, implicating it in cytoskeletal changes during apoptosis. PAK3 is expressed at high levels in post-mitotic neurons of the developing post-natal cerebral cortex and hippocampus, and is the mutant gene thought responsible for non-syndromic X-linked mental retardation.
Sinónimos : Anti-IDDMSSD; Anti-PAKalpha; Anti-alpha-PAK; Anti-p65-PAK
Armazenamento : -20°C
Embalagem : 1X1EA