Anti-phospho-TrkA (pTyr490) antibody produced in rabbit

Descrição detalhada : TrkA belongs to the Trk proto-oncogene family and is expressed mainly in central and peripheral nervous systems. When TrkA binds to NGF, it autophosphorylates tyrosine residues like-Tyr490, Tyr674, Tyr675, Tyr751, and Tyr785 and subsequently activates many downstream effector proteins. Defects in TrkA lead to congenital insensitivity to pain with anhidrosis. Anti-phospho-TrkA (pTyr490) antibody can be used in immunocytochemistry (1:100, using cultured cells). It is also useful in identifying endogenous levels of phosphorylated Tyr490 in TrkA, TrkB and TrkC. Rabbit anti- phospho-TrkA (pTyr490) antibody is reactive in mouse, human and rat.
Sinónimos : Anti-MTC; Anti-TRK; Anti-TRK1; Anti-TRKA; Anti-Trk-A; Anti-p140-TrkA
Armazenamento : -20C
Embalagem : 1X.1ML