Anti-Podoplanin antibody produced in rabbit

Descrição detalhada : Podoplanin (PDPN) is a transmembrane sialoglycoprotein. It consists of 162 amino acids and is part of the type-1 transmembrane sialomucin-like glycoprotein family. The protein is expressed in various tissues. The PDPN gene is localized on human chromosome 1p36.21., Podoplanin is an integral membrane mucoprotein present on the surface of podocytes in kidney glomeruli and the parietal cells of the glomerular Bowman?s capsule. It is a single membrane-spanning protein composed of a heavily glycosylated extracellular domain and a short intracytoplasmic tail. Podoplanin, also named E11 antigen, is present in normal, inflammatory and neoplastic lymphatic capillary endothelium. It is expressed selectively by dermal microvascular lymphatic endothelial cells but not by blood vascular endothelial cells.
Sinónimos : Anti-Aggrus; Anti-GP36; Anti-Glycoprotein, 36-KD; Anti-OTS8; Anti-T1alpha gene; Anti-T1A; Anti-T1A2
Armazenamento : -20C
Embalagem : 1X200UL