Anti-Podoplanin antibody, RAT monoclonal

Descrição detalhada : Monoclonal Anti-Podoplanin (rat IgG2a isotype) is derived from the hybridoma NZ-1.2 produced by the fusion of mouse myeloma cells and splenocytes from CD rat immunized with platelet-aggregation-stimulating (PLAG) domain of podoplanin. Podoplanin (Aggrus) is an integral membrane mucoprotein present on the surface of podocytes in kidney glomeruli and the parietal cells of the glomerular Bowman?s capsule. It is a single membrane-spanning protein composed of a heavily glycosylated extracellular domain and a short intracytoplasmic tail. The extracellular domain possesses a platelet aggregation stimulating (PLAG) domain. Podoplanin has been described to be present in normal, inflammatory and neoplastic lymphatic capillary endothelium.
Sinónimos : Anti-AGGRUS; Anti-GP36, glycoprotein, 36-KD; Anti-GP40; Anti-Gp38; Anti-OTS8; Anti-T1A; Anti-T1A-2
Armazenamento : -20C
Embalagem : 1X200UL