Anti-PORCN Antibody, clone 15G12.1

Descrição detalhada : PORCN is a multi-pass endoplasmic reticulum protein involved in the processing of wingless and other Wnt proteins that facilitate their secretion from Wnt-producing cells. Studies have shown mutations in the genes that encode for PORCN cause a pleiotropic X-linked dominant disorder, focal dermal hypolasia (FDH, also known as Goltz syndrome). Skeletal abnormalities such as syndactyly, ectordactyly, and brachydactyly, and some cases of osteopathia striata have also been attibuted to PORCN abnormalities.
Sinónimos : Probable protein-cysteine N-palmitoyltransferase porcupine, Protein MG61
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA